Histopathological Spectrum of Lesions In Nephrectomy Specimens In Tertiary Care Hospital

Abstract

Introduction: The nephrectomy is indicated in unilateral  end stage renal diseases due to: chronic infections, obstructive uropathy, calculus associated with hydro and pyonephrosis.  Nephrectomy is also indicated in unilateral renal neoplasms, renal cell carcinoma being the most common tumor. Aims & Objectives: The study was undertaken to analyze the spectrum of histopathological lesions in nephrectomy specimens in the surgical pathology section. To attempt clinico- pathological correlation and compare results of our institute with other centers.  Materials & Methods. Over the period of 4 years i.e. June 2014 to June 2018, a total of 32 nephrectomy specimens were received. The histopathological findings were reviewed and relevant data was analyzed.  Results: Out of the total of 32 nephrectomy specimens, the number of non-neoplastic conditions (17) was slightly higher than neoplastic cases. Chronic pyelonephritis was the most frequent benign lesion. Amongst the neoplastic lesions, renal cell carcinoma accounted for 10 (31.25%) cases with varied histomorphological sub-types.  Conclusion:   The present series gives an insight into spectrum of histopathological lesions in nephrectomy specimens at tertiary care hospital. It highlights the clinical significance of clinic-radiological and histopathological correlation.