Severe Vitamin B12 Deficiency Leading to Cerebral Atrophy
Keywords:
Vitamin B12 deficiency, Cerebral atrophyAbstract
Vitamin B deficiency is rare disorder in infants and is generally due to vitamin B12 (cobalamin) deficiency in mother which is usually secondary to pernicious anemia, strict vegetarian diet and malnourishment. Neurological symptoms of vitamin B12 deficiency in infants include irritability, failure to thrive, hypotonia and development regression/ delay. We report a 9-month old infant with insidious developmental regression hypotonic macrocytic anemia and generalized cerebral atrophy on CT scan brain which is markedly improved after vitamin B12 administration.
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