Antibiotic Usage & Rational Guideline Practices In Neonatal Sepsis

Authors

  • Dr. Pradeep Suryawanshi

Keywords:

Early onset sepsis (EOS), Late onset sepsis (LOS), Extended Spectrum Beta Lactamase

Abstract

Antibiotics are being extensively used in India today leading to emergence of multi-drug resistant pathogens, and increased incidence of fungal sepsis. A rational antibiotic policy needs to be in place to prevent the emergence of drug resistant strains. This review covers the common organisms causing neonatal sepsis in India, rationale for selection of antimicrobial agents, duration of therapy and the suggested steps to prevent antimicrobial resistance.

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References

Philip AG, ewill JR. Early diagnosis of neonatal sepsis. Pediatrics 1980; 65: 1036-1041

Remington JS, Klein JO eds. Infectious Diseases of the Fetus and Neonate. 7th Ed Philadeolphia, WB Saunders Company, 2010. Pg. 235.

AK Deorari Neonatal Sepsis: Manageble daunting issue for India. Journal of Neonatology. 2009, 23:7-11.

Zaidi AK, Huskins WC, Thaver D, Bhutta ZA, Abbas Z, Goldmann DA. Hospital- acquired neonatal infections in developing countries. Lancet 2005; 365:1175-1188.

Thaver D, Zaidi AK. Burden of neonatal infections in developing countries: a review of evidence from community based studies. Padiatr Infect Dis J 2009; 28:S3-S9.

Report 2002-2003. National Neonatal Perinatal Database Network. New Delhi. National 1 Neonatology Forum of India

Bang AT, Reddy HM, Baitule SB, et al. The incidence of morbidities in a cohort of neonates in rural Gadchiroli, India: seasonal and temporal variation and a hypothesis about prevention. J Perinatol. 2005; 25:S18-S28.

Stoll BJ. Neonatal infections: a global perspective. In: Remington JS, Klein JO, eds. Infectious diseases of the fetus & newborn infant. 5th edn. Philadelphia: WB Saunders Company, 2001.p.139-168.)

Rasaily R. Epidemiology of Neonatal Infections: Community Experience. Journal of Neonatology.2009; 23:12-21.

Thaver D, Ali SA, Zaidi AK. Antimicrobial resistance among neonatal pathogens in developing countries. Pediatr Infect Dis J 2009; 28:319-321

Isaacs D. Neonatal sepsis: the antibiotic crisis. Indian Pediatr 2005; 42:9-13.

Srinivas Murki. Antibiotic usage and microbial resistance: Indian Scenario. Journal of Neonatology 2009; 23: 53-56

Saili A, Kumar A. Rational use of Antibiotics. Journal of Neonatology 2007;21:13-16

Sehgol R, Goind R. Chellani H, Agarwal Extended spectrum beto

loctomase produeir Grom-negative bocterio: clinical profile 9

utcome in a neonatal tntensive core unit. Ann rop Paediatr 2007, 27:45- 54

Lee J, Pai H, Kim YK, Kim NH, Eun BW, Kang HJ. al. Control of extended specirum beta lactamase producing E. Coli ond Klebsiella pneumoniae in a children's hospital by changing ontimicrobial

ogent usoge policy. Journal of Antimicrobi Chemotherapy 2007; 60:629-637

Jeevo Sankar M, Sankar J, Chowla D, Nangia S. Antibiotic usage in neonates- Guidelines and Current Practices. Journal of Neonatology. 2009 22:68-77.

Escobar GJ, Li DK, Armstrong MA, et al. Neonatal sepsis workups in infants >/=2000 grams at birth: A population based study. Pediatrics 2000, 106:256-263.

Polin RA, Parravicini E, Regan JA, Taeusch Hw Bacterial sepsis and meningitis. In: Taeusch HWw, Ballard RA, Gleason CA (eds): Avery's Diseases of the Newborn, 8th ed Philadelphia, Saunders,

, pp.562-4.

Gerdes JS. Diagnosis and management of bacterial infections in the neonate. Pediatr Clin North Am 2004; 51:939-959.

Gerdes Js. Clinicopathologic approach to the diagnosis of neonatal sepsis. Clin Perinatol 1991; 18:361-381.

Squire E., Favara B., Todd J.: Diagnosis of neonatal bacterial infection: hematologic and pathologic findings in fatal and nonfatal cases.

Pediatrics 1979; 64:60.

Remington JS, Klein JO eds. Infectious Diseases of the Fetus and Neonate. 7th Ed Philadelphia, WB Saunders Company, 2010. Pg.255-259

Bryan C.S., et al: Gentamicin vs. cefotaxime tor therapy of neonatal sepsis. Am. J. Dis Child. 1985; 139:1086.

Manzoni P, et al: Risk factors for progression to invasive fungal infection in preterm neonate with fungal colonization.

:2359-2364

Gordon A, Jeffery HE. Antibiotic regimens fo suspected late onset sepsis in newborn infants Cochrane Database of Systematic Reviews 2005,

Issue 3 Art No.: CD004501.

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Published

2014-03-10

How to Cite

Suryawanshi , D. P. . . . . . . . . . (2014). Antibiotic Usage & Rational Guideline Practices In Neonatal Sepsis. VIMS Health Science Journal, 1(1), 33–40. Retrieved from https://vimshsj.edu.in/index.php/main/article/view/208

Issue

Vol. 1 No. 1 (2014): March

Section

Review Articles

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