Chronic Kidney Diseases (CKD) is a worldwide public health problem. Chronic renal failure patients requires treatment with dialysis or transplantation is the most visible outcome of CKD. The present study was aimed to determine the aspartate transaminase (AST) and alanine transaminase (ALT) levels with baseline parameters in patients with chronic kidney diseases. Total 85 patients were studied in between age group 40 to 70 years. After applying the inclusion and exclusion criteria, a total of 50 chronic kidney disease patients were eligible for the study. The data was collected and compared with 50 age and sex matched healthy controls from the same age group. The statistical analysis was done using SPSS 16.0 software. All the patients were assessed with baseline parameters like RBS (Random Blood Sugar), blood urea, creatinine, total cholesterol and liver enzymes such as AST and ALT. the concentrations of RBS, blood urea, creatinine total cholesterol and were significantly elevated (P<0.001) and AST along with ALT were significantly declined when compared with control group. The serum transaminase levels were declined significantly in patients with kidney diseases on hemodialysis than normal renal function patients. It has a multifactorial origin.
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