Multisystem Inflammatory Syndrome in Children (MIS-C): A Case Report
DOI:
https://doi.org/10.46858/vimshsj.9105Keywords:
MIS-C, SARS-CoV-2, Kawasaki diseaseAbstract
We are in the midst of an unprecedented global pandemic of coronavirus disease (COVID-19), caused by the novel coronavirus SARS-CoV-2. Although, initially thought to a?ect children less severely, 1–3 SARS-CoV-2 infection has recently been associated with a novel set of clinical manifestations presently called multisystem in?ammatory syndrome in children (MIS-C)4 as shown a rapid increment in cases across the world among the pediatric population. Here, we bring a case report, followed up in the rural tertiary care hospital.
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Kest H, Kaushik A, DeBruin W, Colletti M, Goldberg D. Multisystem inflammatory syndrome in children (MIS-C) associated with 2019 novel coronavirus (SARS-CoV-2) infection. Case reports in pediatrics. 2020 Jul 18;2020.
Dong Y, Mo X, Hu Y, Qi X, Jiang F, Jiang Z, Tong S. Epidemiology of COVID-19 among children in China. Pediatrics. 2020 Jun 1;145(6).
Covid CD, Team R, Covid CD, Team R, COVID C, Team R, Bialek S, Gierke R, Hughes M, McNamara LA, Pilishvili T. Coronavirus disease 2019 in children—United States, february 12–april 2, 2020. Morbidity and Mortality Weekly Report. 2020 Apr 10;69(14):422.
Kest H, Kaushik A, DeBruin W, Colletti M, Goldberg D. Multisystem inflammatory syndrome in children (MIS-C) associated with 2019 novel coronavirus (SARS-CoV-2) infection. Case reports in pediatrics. 2020 Jul 18;2020.
American College of Cardiology. ACC clinical bulletin: COVID-19 clinical guidance for the cardiovascular care team. Reviewed March 6, 2020.
Zhu N, Zhang D, Wang W, Li X, Yang B, Song J, Zhao X, Huang B, Shi W, Lu R, Niu P. A novel coronavirus from patients with pneumonia in China, 2019. New England journal of medicine. 2020 Jan 24.
Huang C, Wang Y, Li X, Ren L, Zhao J, Hu Y, Zhang L, Fan G, Xu J, Gu X, Cheng Z. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. The lancet. 2020 Feb 15;395(10223):497-506.
Yonker LM, Shen K, Kinane TB. Lessons unfolding from pediatric cases of COVID?19 disease caused by SARS?CoV?2 infection. Pediatric pulmonology. 2020 May;55(5):1085.
Dong Y, Mo X, Hu Y, Qi X, Jiang F, Jiang Z, Tong S. Epidemiology of COVID-19 among children in China. Pediatrics. 2020 Jun 1;145(6).
Xiao F, Tang M, Zheng X, Liu Y, Li X, Shan H. Evidence for gastrointestinal infection of SARS-CoV-2. Gastroenterology. 2020 May 1;158(6):1831-3.
Panupattanapong S, Brooks EB. New spectrum of COVID-19 manifestations in children: Kawasaki-like syndrome and hyperinflammatory response. Cleveland Clinic Journal of Medicine. 2020 Dec 31.
Verdoni L, Mazza A, Gervasoni A, Martelli L, Ruggeri M, Ciuffreda M, Bonanomi E, D'Antiga L. An outbreak of severe Kawasaki-like disease at the Italian epicentre of the SARS-CoV-2 epidemic: an observational cohort study. The Lancet. 2020 Jun 6;395(10239):1771-8.
Riphagen S, Gomez X, Gonzalez-Martinez C, Wilkinson N, Theocharis P. Hyperinflammatory shock in children during COVID-19 pandemic. The Lancet. 2020 May 23;395(10237):1607-8.
Levin M. Childhood multisystem inflammatory syndrome—a new challenge in the pandemic. New England Journal of Medicine. 2020 Jul 23;383(4):393-5.
Kato H, Sugimura T, Akagi T, Sato N, Hashino K, Maeno Y, Kazue T, Eto G, Yamakawa R. Long-term consequences of Kawasaki disease: a 10-to 21-year follow-up study of 594 patients. Circulation. 1996 Sep 15;94(6):1379-85.
Wilson W. American Heart Association Rheumatic Fever, Endocarditis, and Kawasaki Disease Committee; American Heart Association Council on Cardiovascular Disease in the Young; American Heart Association Council on Clinical Cardiology; American Heart Association Council on Cardiovascular Surgery and Anesthesia; Quality of Care and Outcomes Research Interdisciplinary Working Group. Circulation. 2008;118:887-96.
Riphagen S, Gomez X, Gonzalez-Martinez C, Wilkinson N, Theocharis P. Hyperinflammatory shock in children during COVID-19 pandemic. The Lancet. 2020 May 23;395(10237):1607-8.
Mahase E. Covid-19: concerns grow over inflammatory syndrome emerging in children.
Toubiana J, Poirault C, Corsia A, Bajolle F, Fourgeaud J, Angoulvant F, Debray A, Basmaci R, Salvador E, Biscardi S, Frange P. Kawasaki-like multisystem inflammatory syndrome in children during the covid-19 pandemic in Paris, France: prospective observational study. bmj. 2020 Jun 3;369.
Whittaker E, Bamford A, Kenny J, Kaforou M, Jones CE, Shah P, Ramnarayan P, Fraisse A, Miller O, Davies P, Kucera F. Clinical characteristics of 58 children with a pediatric inflammatory multisystem syndrome temporally associated with SARS-CoV-2. Jama. 2020 Jul 21;324(3):259-69.
Kawasaki T, Kosaki F, Okawa S, Shigematsu I, Yanagawa H. A new infantile acute febrile mucocutaneous lymph node syndrome (MLNS) prevailing in Japan. Pediatrics. 1974 Sep;54(3):271-6.
Ramcharan T, Nolan O, Lai CY, Prabhu N, Krishnamurthy R, Richter AG, Jyothish D, Kanthimathinathan HK, Welch SB, Hackett S, Al-Abadi E. Paediatric inflammatory multisystem syndrome: temporally associated with SARS-CoV-2 (PIMS-TS): cardiac features, management and short-term outcomes at a UK tertiary paediatric hospital. Pediatric cardiology. 2020 Oct;41(7):1391-401.
Mez J, Daneshvar DH, Kiernan PT, Abdolmohammadi B, Alvarez VE, Huber BR, Alosco ML, Solomon TM, Nowinski CJ, McHale L, Cormier KA. Clinicopathological evaluation of chronic traumatic encephalopathy in players of American football. Jama. 2017 Jul 25;318(4):360-70.
Rowley AH. Understanding SARS-CoV-2-related multisystem inflammatory syndrome in children. Nature Reviews Immunology. 2020 Aug;20(8):453-4.
Martinez OM, Bridges ND, Goldmuntz E, Pascual V. The immune roadmap for understanding multi-system inflammatory syndrome in children: opportunities and challenges. Nature medicine. 2020 Dec;26(12):1819-24.
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Copyright (c) 2022 Dr. Pranita Tambe, Dr. Ganesh Misal, Dr. Suresh Waydande
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