Generalised Pustular Psoriasis Masquerading as Lepromatous Leprosy: A Case Report

Authors

  • Dr. Aishwarya Kitture DVVPFs Medical College & Hospital, Ahmednagar-414111, Maharashtra, India
  • Dr. Vishal Indurkar
  • Dr. Anamika Wagh
  • Dr. Ramesh Gosavi

DOI:

https://doi.org/10.46858/vimshsj.9206

Keywords:

Psoriasis, Generalised Pustular Psoriasis, Leprosy, Methotrexate

Abstract

The relationship between psoriasis and leprosy is debatable since ages. The varied clinical manifestations of leprosy may resemble other skin diseases, but there is no documented literature of skin lesions of psoriasis mimicking leprosy. We report a case of generalised pustular psoriasis (GPP) presented with the lepromatous leprosy like clinical features in a 60 year old male. The histopathological examination confirmed the diagnosis. Patient was then treated with Methotrexate 7.5mg weekly and showed improvement in subsequent visits. We report this rare possibility to raise awareness among clinicians to allow accurate diagnosis since leprosy still carries stigma in society.

Downloads

Download data is not yet available.

References

Choon SE, Lai NM, Mohammad NA, Nanu NM, Tey KE, Chew SF: Clinical profile, morbidity, and outcome of adult-onset generalized pustular psoriasis: analysis of 102 cases seen in a tertiary hospital in Johor, Malaysia. Int J Dermatol 2014;53:676-684.

Gudjonsson JE; Elder JT: Psoriasis; in Goldsmith LA, Katz SI, Gilchrest BA, Paller AS, Leffell DJ, Wolff K (eds): Fitzpatrick's Dermatology in General Medicine, ed 8. New York, McGraw-Hill, 2012, vol 22, pp 197-231.

Guerreiro de Moura C.A.G., de Assis L.H., Góes P.a · Rosa F., Nunes V., Gusmão Í.M., Cruz C.M.S. A Case of Acute Generalized Pustular Psoriasis of von Zumbusch Triggered by Hypocalcemia. Case Reports in Dermatology. 2015;7:345-351.

Johnston A, Xing X, Wolterink L, et al.: IL-1 and IL-36 are dominant cytokines in generalized pustular psoriasis. J Allergy Clin Immunol. 2017, 140:109-120. 10.1016/j.jaci.2016.08.056.

Kumar B, Raychaudhuri SP, Vossough S, Farber EM. The rare coexistence of leprosy and psoriasis. Int J Dermatol 1992;31:551-4.

Ganapati R, Deshpande DH, Chulawala RG. Some interesting disease combinations — Report on two cases. Lepr India 1976;48:428.

Bassukas ID, Gaitanis G, Hundeiker M. Leprosy and the natural selection for psoriasis. Med Hypotheses 2012;78:183-90.

Takahashi H, Manabe A, Ishida-Yamamoto A, Hashimoto Y, Iizuka H. Aberrant expression of apoptosis-related molecules in psoriatic epidermis. J Dermatol Sci 2002;28:187-97.

Dogra S, Kaur I, Kumar B. Leprosy and psoriasis: An enigmatic relationship. Int J Lepr Other Mycobact Dis 2003;71:341-3.

Downloads

Published

2022-06-30

How to Cite

Kitture, D. A., Indurkar, D. V., Wagh, D. A., & Gosavi, D. R. . (2022). Generalised Pustular Psoriasis Masquerading as Lepromatous Leprosy: A Case Report. VIMS Health Science Journal, 9(2), 55–57. https://doi.org/10.46858/vimshsj.9206

Issue

Section

Case Report

Most read articles by the same author(s)