NIPAH Virus
Keywords:
Nipah virus, RNA Virus, Paramyxoviridae familyAbstract
Nipah virus (NiV) infection is a newly emerging zoonosis that causes severe disease in both animals and humans. The natural host of the virus are fruit bats of the Pteropodidae Family, Pteropus genus. NiV was first identified during an outbreak of disease that took place in Kampung Sungai Nipah, Malaysia in 1998. On this occasion, pigs were the intermediate hosts. In Bangladesh in 2004, humans became infected with NiV as a result of consuming date palm sap that had been contaminated by infected fruit bats. Human-to-human transmission has also been documented, including in a hospital setting in India.
NiV infection in humans has a range of clinical presentations, from asymptomatic infection to acute respiratory syndrome and fatal encephalitis. NiV is also capable of causing disease in pigs and other domestic animals. There is no vaccine for either humans or animals. The primary treatment for human cases is intensive supportive care.
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Outbreak of Hendra-like virus – Malaysia and Singapore, 1998-1999. MMWR Morb Mortal Wkly Rep 1999;48:265-269[Erratum, WR Morb Mortal Wkly Rep 1999;48:339.
Update: outbreak of Nipah virus – Malaysia and Singapore, 1999. MMWR Morb Mortal Wkly Rep 1999;48: 335-337.
Chua KB, Goh KJ, Wong KT, et al. Fatal encephalitis due to the Nipah virus among pig-farmers in Malaysia. Lancet 1999;354:1257-1259.
.Lee KE, Umapathi T, Tan CB, et al. The neurological manifestations of Nipah virus encephalitis, a novel paramyxovirus. Ann Neurol 1999;46:428-432.
Paton NI, Leo YS, Zaki SR, et al. Outbreak of Nipah-virus infection among abattoir workers in Singapore, Lancet 1999;354:1253-1256.
O’Sullivan JD, Allworth AM, Paterson DL, et al. Fatal encephalitis due to novel paramyxovirus transmitted from horses. Lancet 1997;349:93-95.
Selvey LA, Wells RM, McCormack JG, et al. Infection of human and horses by a newly described morbillivirus. Med J Aust 1995; 162:642-645.
Thongcharoen P. Japanese encephalitis virus encephalitis: an overview. Southeast Asian J Trop Med Public Health 1989;20:559-573.
Philbey, A. W. et al. An apparently new virus (family paramyxoviridae) infection for pigs, humans, and fruit bats. Emerg, Infect, Dis.4,269-271 (1998).
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